About Us

The Town of St. Matthews

The Town of St. Matthews is located in Calhoun County, South Carolina United States of America. It is the County seat of Calhoun County. It is offers a small southern town appeal just 32 miles south of the State Capital and less than 10 miles from Interstate 26. US route 601 passes through the Town, leading northeast 51 miles to Camden and southwest 13 miles to Orangeburg.  SC Highway 6 crosses US 601 in the center of Town and leads west 7 miles to Interstate 26 and southeast 22 miles to Interstate 95 near Santee.

Population: 2,021

Elevation: 357 ft. 

County: Calhoun

Our Story

In the 1730’s, St. Matthews was established as the township of Amelia by Gov. Robert Johnson. Over a century later, in 1841, the Town of St. Matthews was settled. What began as a quaint farming town known for its cotton plantations is now home to a variety of shops, restaurants and other attractions.